Find recruiting clinical trials for acne in the UK — including novel topical treatments, microbiome-based therapies, laser and light-based treatments, and next-generation systemic drugs. See your treatment pathway and where trials fit in.
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Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
Comedones and mild inflammatory lesions
Standard: Benzoyl peroxide, topical retinoids, salicylic acid
Widespread inflammatory papules and pustules
Standard: Topical retinoid + antibiotic, oral antibiotics, combined oral contraceptive
Nodules and cysts with scarring risk
Standard: Oral isotretinoin (Roaccutane), spironolactone, hormonal therapy
Treatment-resistant or scarring acne
Standard: High-dose isotretinoin, dermatology referral, procedural treatments
Trials testing topical and oral probiotic formulations, bacteriophage therapy targeting Cutibacterium acnes, and microbiome-balancing skincare to treat acne without antibiotics.
New topical drugs including clascoterone (first topical anti-androgen), trifarotene (new retinoid), and nanoparticle delivery systems for better skin penetration with fewer side effects.
Photodynamic therapy, intense pulsed light (IPL), and fractional laser treatments being tested for active acne and acne scar revision.
Topical and systemic anti-androgen treatments that target the hormonal drivers of acne without the side effects of oral isotretinoin.
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No. Adult acne is increasingly common and many trials specifically recruit adults aged 18-45. Some trials also focus on acne scarring treatments for any age group.
Most trials require you to have stopped isotretinoin for at least 1-6 months before joining, as it affects the skin for some time after stopping. Check each trial's specific washout period.
Yes. Several UK trials are testing laser resurfacing, microneedling with growth factors, and injectable treatments for atrophic acne scars. These are often in dermatology departments at major hospitals.
Yes. Some trials are investigating tea tree oil formulations, dietary interventions (low-glycaemic diets), omega-3 supplements, and traditional Chinese medicine approaches for acne management.
Use our search above to find trials matching your condition and location. Review eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.