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Anxiety Clinical Trials

Find recruiting clinical trials for anxiety in the UK — including generalised anxiety disorder (GAD), PTSD, panic disorder, and social anxiety. See where trials fit into your treatment journey.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

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Anxiety Treatment Pathway

See where clinical trials fit into your treatment journey

1st Line

Initial treatment

Standard: SSRI (Sertraline, Escitalopram) + CBT (Cognitive Behavioural Therapy)

2nd Line

After inadequate response

Standard: Switch SSRI/SNRI or add Buspirone

PTSD-Specific

For trauma-related anxiety

Standard: Trauma-focused CBT, EMDR, or Prazosin for nightmares

Refractory

After multiple treatment failures

Standard: Clinical trial, augmentation strategies, or specialist referral

About Anxiety

Generalised Anxiety Disorder

Excessive, persistent worry about multiple areas of life lasting 6+ months. Often co-exists with depression.

PTSD

Post-traumatic stress disorder. Develops after experiencing or witnessing a traumatic event. Symptoms include flashbacks, hypervigilance, and avoidance.

Panic Disorder

Recurrent unexpected panic attacks with persistent worry about future attacks. May occur with or without agoraphobia.

Search Anxiety Trials

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Frequently Asked Questions

Many trials allow concurrent medication, especially augmentation studies. Some require a stable dose for a minimum period. Check the specific trial eligibility criteria or ask the trial team.

Yes. Many trials investigate digital therapies (apps, online CBT), neurostimulation (TMS, tDCS), mindfulness-based interventions, and novel psychotherapy approaches. Not all trials involve medication.

GAD trials focus on general worry and anxiety symptoms. PTSD trials specifically target trauma-related symptoms like flashbacks, nightmares, and hypervigilance. Some trials accept multiple anxiety diagnoses.

Read the eligibility criteria carefully. Consider the time commitment, visit frequency, and whether the intervention aligns with your treatment goals. Discuss it with your GP or psychiatrist.

How to Join a Anxiety Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

Related Comparisons

🗺️ Related Pathway: Mental Health Pathway