Find recruiting clinical trials for bipolar disorder in the UK — including bipolar I, bipolar II, and rapid cycling. See treatment pathways from acute episodes to maintenance therapy.
Free to use — Live data from ClinicalTrials.gov — Updated hourly
Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
Treating manic or mixed episodes
Standard: Antipsychotics (Olanzapine, Quetiapine), Mood stabilisers (Lithium, Valproate)
Treating depressive episodes without triggering mania
Standard: Quetiapine, Lamotrigine, Lurasidone, or Lithium
Preventing future episodes
Standard: Lithium, Valproate, Olanzapine, or Lamotrigine long-term
When standard treatments have not worked
Live results from ClinicalTrials.gov — recruiting now in the UK
Yes. Bipolar depression trials are a major focus, testing new agents that treat depressive episodes without triggering mania. Current trials include novel antipsychotics, glutamate modulators, and circadian rhythm interventions.
Many maintenance trials specifically recruit stable patients to test whether new treatments prevent episodes better than current medication. Some trials allow continued stable dosing of certain medications while adding the experimental therapy.
Trials span acute mania, bipolar depression, maintenance prevention, rapid cycling, and comorbid conditions. Treatment approaches include novel antipsychotics, mood stabilisers, neuromodulation, psychotherapy, and chronobiology interventions.
Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.