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Chronic Kidney Disease Clinical Trials

Find recruiting clinical trials for chronic kidney disease (CKD) in the UK — including stage 3-5, dialysis, and post-transplant studies. See treatment pathways and where trials fit in.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

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Chronic Kidney Disease Treatment Pathway

See where clinical trials fit into your treatment journey

Stage 3 — Early CKD

eGFR 30-59, moderate decline

Standard: ACEi/ARB, SGLT2 inhibitor (Dapagliflozin), blood pressure control

Stage 4 — Advanced CKD

eGFR 15-29

Standard: Optimise renoprotective therapy, prepare for renal replacement

Stage 5 — Dialysis

End-stage kidney disease

Standard: Haemodialysis, peritoneal dialysis, or kidney transplant

About Chronic Kidney Disease

Diabetic Kidney Disease

Kidney damage caused by diabetes — the most common cause of CKD. SGLT2 inhibitors have revolutionised treatment, slowing progression significantly.

IgA Nephropathy

The most common primary glomerulonephritis. New targeted therapies including Nefecon and targeted-release budesonide are showing promise.

Post-Transplant

After kidney transplantation. Trials focus on improving graft survival, reducing immunosuppression side effects, and preventing rejection.

Search Chronic Kidney Disease Trials

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Frequently Asked Questions

SGLT2 inhibitors (Dapagliflozin, Empagliflozin) were originally diabetes drugs but are now proven to slow kidney disease progression regardless of diabetes status. They are a major breakthrough in CKD treatment.

Yes. Many trials specifically target non-diabetic CKD including IgA nephropathy, polycystic kidney disease, FSGS, and other glomerular diseases. SGLT2 inhibitors are now being studied in these populations too.

Some trials specifically recruit dialysis patients, studying new dialysis techniques, anaemia management, phosphate binders, or transitions to transplant. Check eligibility criteria for dialysis-specific trials.

How to Join a Chronic Kidney Disease Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

Related Comparisons

🗺️ Related Pathway: Cardiovascular & Metabolic Pathway