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Chronic Pain & Fibromyalgia Clinical Trials

Find recruiting clinical trials for chronic pain and fibromyalgia in the UK — including neuropathic pain, musculoskeletal pain, and central sensitisation syndromes. See treatment pathways and emerging approaches.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

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Chronic Pain & Fibromyalgia Treatment Pathway

See where clinical trials fit into your treatment journey

Mild-Moderate Pain

First-line management approaches

Standard: NSAIDs, physiotherapy, CBT for pain, graded exercise

Neuropathic Pain

Nerve-related pain conditions

Standard: Gabapentin, Pregabalin, Duloxetine, Amitriptyline

Fibromyalgia

Widespread pain with central sensitisation

Standard: Duloxetine, Pregabalin, Amitriptyline, CBT, exercise

Advanced / Refractory

When standard treatments have not worked

Options: Neuromodulation, specialist pain clinics, experimental treatments

Search Chronic Pain & Fibromyalgia Clinical Trials

Live results from ClinicalTrials.gov — recruiting now in the UK

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Frequently Asked Questions

Yes — this is a major research focus. Non-opioid trials include novel sodium channel blockers, anti-NGF antibodies, cannabinoid-based medicines, neuromodulation devices, VR therapy, and digital pain management programmes.

Fibromyalgia trials specifically target central sensitisation (amplified pain processing). General chronic pain trials may focus on neuropathic pain (nerve damage), nociceptive pain (tissue damage), or mixed pain types. Some trials accept both.

Some trials allow stable medication regimens, while others require a washout period. Many non-pharmacological trials (devices, digital therapies, psychological approaches) allow concurrent medication. Check specific trial criteria.

How to Join a Chronic Pain & Fibromyalgia Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

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🗺️ Related Pathway: Musculoskeletal & Pain Pathway