Find recruiting clinical trials for dementia in the UK — including vascular dementia, Lewy body dementia, frontotemporal dementia, and mixed dementia. See treatment approaches from early intervention to symptom management and where trials fit in.
Free to use — Live data from ClinicalTrials.gov — Updated hourly
Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
Caused by reduced blood flow to the brain, often after stroke
Standard: Blood pressure management, antiplatelet therapy, lifestyle changes
Characterised by visual hallucinations, motor symptoms, and fluctuating cognition
Standard: Cholinesterase inhibitors, physical therapy, symptom management
Affects behaviour, personality, and language — often diagnosed younger
Standard: Behavioural management, speech therapy, SSRIs for behavioural symptoms
Early memory and thinking problems that may progress to dementia
Standard: Cognitive stimulation, lifestyle interventions, monitoring
While most approved for Alzheimer's, some trials are testing whether these drugs benefit other forms of dementia, particularly mixed dementia with amyloid pathology.
Trials testing intensive blood pressure management, anti-inflammatory drugs, and lifestyle interventions to slow vascular dementia progression.
Emerging drugs targeting brain inflammation (TSPO, microglial activation) that may slow multiple types of dementia.
Cognitive training apps, VR-based rehabilitation, and AI-driven monitoring tools being tested to maintain cognitive function and independence.
Loading trials from ClinicalTrials.gov...
Dementia is an umbrella term for a decline in cognitive function severe enough to affect daily life. Alzheimer's is the most common cause. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia — each with different causes and treatments.
Yes. While most dementia drug trials have focused on Alzheimer's, there is growing research into vascular dementia, Lewy body dementia, and frontotemporal dementia — including anti-inflammatory drugs, neuroprotective agents, and gene therapies.
Some trials accept participants with moderate to severe dementia, particularly those testing symptom management and quality of life interventions. A legal representative or carer would need to provide consent.
Many trials welcome carer involvement — from accompanying participants to joining studies about carer wellbeing, decision-making support, and technology testing. Contact your local NIHR clinical research network.
Use our search above to find trials matching your condition and location. Review eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.