Find recruiting clinical trials for fibromyalgia in the UK — including novel pain modulators, neuromodulation devices, psychedelic-assisted therapy, and digital cognitive behavioural programmes. See your treatment pathway and where trials fit in.
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Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
Recently diagnosed or mild symptoms
Standard: Exercise programmes, CBT, sleep hygiene, stress management
Symptoms affecting daily function despite lifestyle measures
Standard: Duloxetine, pregabalin, amitriptyline, gabapentin
Persistent symptoms despite multiple treatments
Standard: Multidisciplinary pain management, neuromodulation, specialist referral
Fibromyalgia alongside IBS, chronic fatigue, or depression
Standard: Integrated management addressing overlapping conditions
Trials testing new drugs targeting the central nervous system's pain processing — including dual serotonin-noradrenaline reuptake inhibitors, sodium channel blockers, and neuroinflammation modulators.
Non-invasive brain stimulation (TMS, tDCS) and vagus nerve stimulation to modulate pain pathways in the central nervous system.
Early-phase trials exploring psilocybin and MDMA-assisted therapy for chronic pain conditions including fibromyalgia, focusing on pain perception and psychological wellbeing.
App-based CBT, virtual reality pain management, and AI-driven personalised exercise programmes being tested in UK trials.
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Yes. Some NHS pain clinics participate in fibromyalgia trials, particularly those testing new drugs or digital therapies. Ask your rheumatologist or pain specialist about local research opportunities.
Promising areas include neuroinflammation modulators, vagus nerve stimulation, psychedelic-assisted therapy, and precision medicine approaches that target specific pain pathways based on genetic profiles.
Some trials specifically recruit patients with overlapping conditions. Others may exclude them to isolate treatment effects. Check individual trial eligibility criteria carefully.
Many drug trials use a placebo comparison group, which is standard practice. You would be randomly assigned to receive either the active treatment or placebo, and neither you nor the researchers would know which during the trial.
Use our search above to find trials matching your condition and location. Review eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.