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Leukaemia Clinical Trials

Find recruiting clinical trials for leukaemia in the UK — including AML, ALL, CML, CLL, and myelodysplastic syndrome subtypes. See treatment pathways and where trials fit in.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

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Leukaemia Treatment Pathway

See where clinical trials fit into your treatment journey

AML — Intensive

Acute myeloid leukaemia, fit patients

Standard: Induction chemotherapy (7+3) + consolidation

AML — Lower Intensity

For older or less fit patients

Standard: Azacitidine + Venetoclax or low-dose cytarabine

ALL

Acute lymphoblastic leukaemia

Standard: Multi-agent chemotherapy + CNS prophylaxis, or CAR-T for relapsed

CML

Chronic myeloid leukaemia

Standard: TKI therapy (Imatinib, Dasatinib, Nilotinib)

About Leukaemia

AML

Acute myeloid leukaemia — rapid-growing cancer of myeloid white blood cells. Most common acute leukaemia in adults. Treatment varies by age and fitness.

ALL

Acute lymphoblastic leukaemia — most common childhood cancer but also affects adults. CAR-T cell therapy has transformed relapsed/refractory disease.

CML

Chronic myeloid leukaemia — a success story of targeted therapy. Most patients take daily TKI tablets (like Imatinib) with excellent long-term control.

Search Leukaemia Trials

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Frequently Asked Questions

CAR-T cell therapy engineers your own immune cells to recognise and attack leukaemia. It is approved for relapsed/refractory ALL and being studied in AML and other blood cancers. Multiple UK centres have active CAR-T trials.

Absolutely. Many trials specifically target older or less fit patients, particularly in AML where lower-intensity regimens like Azacitidine + Venetoclax are studied. Age alone is rarely an exclusion.

Yes. Modern trials include targeted therapies (FLT3 inhibitors, IDH inhibitors, BCL2 inhibitors like Venetoclax), immunotherapies (bispecific antibodies, CAR-T), and kinase inhibitors. Many avoid traditional chemotherapy.

Treatment phases range from a few weeks (AML induction) to years (CML TKI therapy). Most trials include a follow-up period of 1-5 years. The trial team will provide a clear timeline.

How to Join a Leukaemia Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

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