Find recruiting clinical trials for obesity in the UK — including GLP-1 receptor agonist therapy, weight management, and bariatric surgery candidates. See treatment pathways and where trials fit in.
Free to use — Live data from ClinicalTrials.gov — Updated hourly
Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
BMI 30+ initial management
Standard: Dietary changes, physical activity, behavioural support
BMI 30+ or BMI 27+ with comorbidities
Standard: GLP-1 agonist (Semaglutide/Wegovy, Tirzepatide/Mounjaro)
BMI 40+ or BMI 35+ with comorbidities
Standard: Gastric bypass, sleeve gastrectomy, or gastric band
The newest and most effective class of weight-loss medications. Semaglutide (Wegovy) and Tirzepatide (Mounjaro) have shown 15-22% body weight reduction in trials.
People with severe obesity who may benefit from surgical intervention. Trials explore new procedures, combination therapies, and long-term outcomes.
When obesity co-exists with type 2 diabetes, cardiovascular disease, or sleep apnoea. Many trials target specific comorbidity combinations.
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Several next-generation treatments are in trials: Retatrutide (triple agonist), CagriSema (combination of semaglutide + cagrilintide), oral GLP-1 tablets, and amylin analogues. These aim for even greater weight loss than current options.
Some trials recruit patients already on GLP-1 therapy to study long-term effects or combination approaches. Others require a washout period. Check individual trial criteria.
Yes. Clinical trials provide the investigational treatment, medical monitoring, and related tests at no cost. You may also receive travel expenses.
Requirements vary. Most trials require BMI 30+ or BMI 27+ with at least one weight-related comorbidity (diabetes, hypertension, sleep apnoea). Some trials target specific BMI ranges.
Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.