Actively Recruiting

Psoriasis Clinical Trials

Find recruiting clinical trials for psoriasis in the UK — including plaque psoriasis, guttate, nail psoriasis, and psoriatic arthritis. See treatment pathways and where trials fit in.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

🎯 Smart Matcher — Find Trials For You

Answer a few questions about your condition and we'll match you to the most relevant clinical trials.

Find My Matches →

Psoriasis Treatment Pathway

See where clinical trials fit into your treatment journey

Mild — Topical

Limited body surface area

Standard: Topical corticosteroids, Vitamin D analogues (Calcipotriol)

Moderate — Phototherapy

Wider body surface area

Standard: UVB phototherapy, or systemic Methotrexate/Ciclosporin

Moderate-Severe — Biologics

Eligible for biologic therapy

Standard: Anti-TNF (Adalimumab), Anti-IL17 (Secukinumab), Anti-IL23 (Guselkumab)

Biologic-Experienced

After prior biologic failure

Standard: Switch biologic class or clinical trial

About Psoriasis

Plaque Psoriasis

The most common form (80-90%). Raised, red, scaly patches typically on elbows, knees, scalp, and lower back.

Nail Psoriasis

Affects fingernails and toenails — pitting, discolouration, and separation from the nail bed. Often overlooked but significantly impacts quality of life.

Psoriatic Arthritis

Joint inflammation associated with psoriasis. About 30% of psoriasis patients develop psoriatic arthritis, which can cause permanent joint damage.

Search Psoriasis Trials

Loading trials from ClinicalTrials.gov...

Frequently Asked Questions

Yes. Clinical trials provide the investigational treatment at no cost. For biologic trials, this can represent significant value as biologics are expensive treatments. You will also receive close monitoring.

Yes. Many trials specifically recruit patients who have failed one biologic class and test switching to a different mechanism of action (e.g., from anti-TNF to anti-IL17 or anti-IL23).

PASI (Psoriasis Area and Severity Index) measures the extent and severity of psoriasis. Most trials use PASI 75 (75% improvement) or PASI 90 as their primary endpoint to measure treatment success.

Yes. Some trials specifically target nail psoriasis or scalp psoriasis, which can be harder to treat with standard therapies. These trials often use specialised scoring systems.

How to Join a Psoriasis Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

Related Comparisons

🗺️ Related Pathway: Autoimmune & Inflammatory Pathway