Actively Recruiting

PTSD (Post-Traumatic Stress Disorder) Clinical Trials

Find recruiting clinical trials for PTSD in the UK — including combat-related, civilian trauma, and complex PTSD. See treatment pathways from first-line therapy to emerging psychedelic approaches.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

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PTSD (Post-Traumatic Stress Disorder) Treatment Pathway

See where clinical trials fit into your treatment journey

First-Line — Psychotherapy

Trauma-focused talking therapies

Standard: Trauma-focused CBT, EMDR

Second-Line — Medication

When therapy alone is insufficient

Standard: Sertraline, Paroxetine (SSRIs)

Emerging — Psychedelics

Novel approaches for treatment-resistant PTSD

Investigational: MDMA-assisted psychotherapy, psilocybin

Treatment-Resistant

When standard treatments have not provided relief

Search PTSD (Post-Traumatic Stress Disorder) Clinical Trials

Live results from ClinicalTrials.gov — recruiting now in the UK

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Frequently Asked Questions

Yes. MDMA-assisted psychotherapy trials are actively recruiting in the UK, following breakthrough therapy designation. These combine controlled MDMA sessions with specialised trauma-focused psychotherapy. Other psychedelic trials using psilocybin are also in development.

Many PTSD trials allow comorbid depression as long as PTSD is the primary diagnosis. Some trials specifically target PTSD with comorbid conditions. Always check specific inclusion/exclusion criteria.

Standard PTSD trials typically focus on single-event trauma. Complex PTSD (C-PTSD) results from prolonged, repeated trauma and may require different approaches. Some trials specifically recruit for C-PTSD, while others accept both.

How to Join a PTSD (Post-Traumatic Stress Disorder) Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

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