Find recruiting clinical trials for tinnitus in the UK — including neuromodulation devices, pharmaceutical treatments, sound therapy innovations, and hearing technology trials. See your treatment pathway and where trials fit in.
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See where clinical trials fit into your treatment journey
Tinnitus lasting less than 6 months
Standard: Hearing assessment, sound therapy, counselling, addressing underlying cause
Persistent tinnitus lasting more than 6 months
Standard: CBT, tinnitus retraining therapy, hearing aids, sound enrichment
Significantly affecting quality of life, sleep, and mental health
Standard: Multidisciplinary management, neuromodulation, specialist ENT referral
Tinnitus accompanied by measurable hearing impairment
Standard: Hearing aids, cochlear implant assessment, combined auditory therapy
Devices using targeted electrical or magnetic stimulation to disrupt tinnitus-related neural activity. Lenire (bimodal neuromodulation) has shown significant results in clinical trials.
Drug trials targeting NMDA receptors, potassium channels, and neuroinflammation pathways. Several compounds are in Phase 2 testing for tinnitus relief.
Personalised sound therapy using AI-generated sounds matched to individual tinnitus profiles, acoustic coordinated reset therapy, and notched music therapy.
Advanced hearing aids with integrated tinnitus masking, cochlear implant trials for single-sided deafness with tinnitus, and bone conduction devices.
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There is currently no universal cure, but several promising approaches are in trials. Bimodal neuromodulation (like the Lenire device) has shown significant tinnitus reduction in clinical studies, and pharmaceutical approaches targeting brain plasticity are advancing.
Some trials recruit participants with mild to moderate tinnitus, particularly those testing preventive or early intervention approaches. The eligibility criteria vary — some require a minimum tinnitus severity score.
It combines sound stimulation through headphones with gentle electrical stimulation of the tongue. The simultaneous stimulation is designed to retrain the brain's auditory circuits and reduce tinnitus perception.
Some NHS audiology and ENT departments participate in tinnitus trials, particularly device studies. Ask your audiologist or ENT consultant about current research opportunities.
Use our search above to find trials matching your condition and location. Review eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.