Find recruiting clinical trials for asthma in the UK — including severe asthma, eosinophilic asthma, and allergic asthma subtypes. See treatment pathways and where trials fit in.
Free to use — Live data from ClinicalTrials.gov — Updated hourly
Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
Regular controller therapy needed
Standard: Low-dose inhaled corticosteroids (ICS)
Symptoms despite low-dose therapy
Standard: Medium-dose ICS + LABA (e.g. Seretide, Symbicort)
Uncontrolled despite high-dose therapy
Standard: Biologics (Omalizumab, Mepolizumab, Dupilumab, Benralizumab)
High eosinophil counts driving inflammation
Standard: Anti-IL5 therapy (Mepolizumab, Benralizumab) or Anti-IL4Rα (Dupilumab)
Requires high-dose medication or biologics. About 5-10% of asthma patients have severe disease that does not respond to standard therapy.
Driven by high levels of eosinophils (a type of white blood cell). Responds well to targeted biologic therapies like anti-IL5 agents.
Triggered by allergens such as pollen, dust mites, or pet dander. May respond to anti-IgE therapy (Omalizumab).
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Yes. Many trials recruit patients with stable, well-controlled asthma to test new prevention strategies, compare treatments, or study long-term outcomes. Your current control level does not exclude you.
Several biologics (Omalizumab, Mepolizumab, Benralizumab, Dupilumab) are available on the NHS for severe eosinophilic asthma. Clinical trials may offer access to newer biologics not yet approved.
Common tests include spirometry (lung function), FeNO (airway inflammation), blood tests for eosinophils and IgE, and sometimes sputum analysis or bronchoscopy depending on the study.
Most asthma trials run 12-52 weeks for treatment studies, with some prevention or long-term safety studies lasting 1-3 years. Phase 3 trials are typically 24-52 weeks.
Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.