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Hepatitis Clinical Trials

Find recruiting clinical trials for hepatitis in the UK — including hepatitis B, hepatitis C, and autoimmune hepatitis. See treatment pathways and where trials fit in.

Free to use — Live data from ClinicalTrials.gov — Updated hourly

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Hepatitis Treatment Pathway

See where clinical trials fit into your treatment journey

Hepatitis B — Treatment

Chronic HBV management

Standard: Entecavir or Tenofovir (antiviral tablets) for viral suppression

Hepatitis B — Cure

Functional cure research

Standard: RNA interference, capsid inhibitors, or therapeutic vaccines

Hepatitis C — DAA

Direct-acting antivirals

Standard: Sofosbuvir/Velpatasvir (Epclusa) — 95%+ cure rate in 8-12 weeks

Autoimmune Hepatitis

Immune-mediated liver inflammation

Standard: Prednisolone + Azathioprine, or Mycophenolate

About Hepatitis

Hepatitis B

Chronic viral infection of the liver. Treatments can suppress the virus effectively, but a functional cure (clearing the virus) remains elusive — many trials aim to achieve this.

Hepatitis C

Curable with modern direct-acting antivirals in 95%+ of cases. However, many people remain undiagnosed. Trials focus on simplified treatment, reinfection, and special populations.

Autoimmune Hepatitis

The immune system attacks the liver. Requires long-term immunosuppression. Some patients are difficult to manage and may benefit from clinical trials.

Search Hepatitis Trials

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Frequently Asked Questions

Yes. Modern direct-acting antivirals (DAAs) cure hepatitis C in over 95% of cases with 8-12 weeks of tablets. Trials are studying even shorter courses and simplified treatment pathways.

A functional cure means sustained loss of hepatitis B surface antigen (HBsAg) without ongoing treatment. Current trials are testing RNA interference, capsid assembly modulators, and therapeutic vaccines to achieve this.

Yes. Hepatitis B and C are more common in people with HIV, and several UK trials specifically study co-infection treatment approaches, drug interactions, and outcomes.

How to Join a Hepatitis Clinical Trial

1

Search

Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.

2

Discuss

Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.

3

Contact

Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.

4

Enrol

If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.

Related Comparisons

🗺️ Related Pathway: Infectious Disease Pathway