Find recruiting clinical trials for HIV/AIDS in the UK — including treatment-naive, treatment-experienced, and PrEP (prevention) studies. See treatment pathways and where trials fit in.
Free to use — Live data from ClinicalTrials.gov — Updated hourly
Answer a few questions about your condition and we'll match you to the most relevant clinical trials.
See where clinical trials fit into your treatment journey
Initial antiretroviral therapy
Standard: Bictegravir/FTC/TAF (Biktarvy) or Dolutegravir-based regimen
After resistance or intolerance
Standard: Regimen optimisation with resistance testing, or novel agents
Eradication or functional cure research
Standard: Latency reversal, gene editing (CRISPR), or immunotherapy approaches
Pre-exposure prophylaxis
Standard: Daily or on-demand PrEP (Tenofovir/Emtricitabine), long-acting injectable (Cabotegravir)
People starting HIV treatment for the first time. Modern ART is highly effective, typically reducing viral load to undetectable within weeks.
People who have developed resistance to some HIV medications. New drug classes like attachment inhibitors and maturation inhibitors offer alternatives.
Pre-exposure prophylaxis — medication taken by HIV-negative people to prevent infection. Trials explore long-acting injectable and implantable options.
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Yes. Several UK trials are investigating HIV cure strategies including latency-reversing agents, broadly neutralising antibodies, gene editing (CRISPR), and therapeutic vaccines. While a cure has not yet been found, progress is being made.
Yes. Cabotegravir + Rilpivirine (Cabenuva) is approved as monthly/bimonthly injections replacing daily pills. Trials are exploring even longer-acting formulations (every 6 months) and new injectable candidates.
Many trials specifically recruit people with undetectable viral load, particularly cure research, treatment simplification studies, and long-term safety trials. Being undetectable is often a requirement.
Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.