Find recruiting clinical trials for Long COVID in the UK — including post-COVID fatigue, cognitive symptoms, exercise intolerance, and recovery studies. See where trials fit in your journey.
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See where clinical trials fit into your treatment journey
Diagnosing Long COVID
Standard: Comprehensive assessment including blood tests, cardiac and respiratory evaluation
Structured recovery programmes
Standard: Pace-guided rehabilitation, cognitive behavioural therapy, breathing exercises
Addressing specific mechanisms
Standard: Antivirals, anti-inflammatory agents, or immunomodulatory therapy
Persistent, disabling fatigue lasting months or years after COVID infection. The most common Long COVID symptom. Pacing and energy management are key.
Difficulty concentrating, memory problems, and mental fatigue. Can significantly impact work and daily activities.
Inability to return to previous exercise levels. Some patients experience post-exertional malaise — symptoms worsening after physical activity.
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Long COVID is generally defined as symptoms persisting more than 12 weeks after COVID infection that cannot be explained by another diagnosis. Common symptoms include fatigue, brain fog, breathlessness, and exercise intolerance.
Current UK trials are investigating antivirals (Nirmatrelvir), anti-inflammatory drugs, immunomodulatory therapies, structured rehabilitation programmes, and treatments targeting specific symptoms like brain fog and exercise intolerance.
Requirements vary. Some trials require documented positive COVID test, while others accept clinical diagnosis based on symptoms. The HEAL-COVID and other major UK trials have different criteria.
Use our search above to find trials that match your condition and location. Review the eligibility criteria carefully.
Talk to your GP or specialist about any trials you are interested in. They can help determine if a trial is appropriate for you.
Reach out to the trial team directly using the contact information on the ClinicalTrials.gov listing. They will guide you through screening.
If you meet the criteria and decide to participate, you will go through informed consent and begin the trial process.